Somatic Metrics Report

In somatic tumor-normal mode, DRAGEN generates separate reports for the tumor and normal samples. Each report is labeled according to the sample type. Tumor sample reports include tumor at the end of the file name, and normal sample reports include normal at the end of the file name. To include both tumor and normal sample results in one file, set the --vc-enable-separate-t-n-metrics option to false. DRAGEN then reports on the aggregate of both samples instead.

DRAGEN generates the following reports:

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coverage_metrics

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contig_mean_cov

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fine_hist

•

hist

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overall_mean_cov

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ploidy

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cov_report (if requested)

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full_res (if requested)

•

gc_metrics (if requested)

If a target bed is included in the run or the option --qc-region-coverage-region-i (where i is 1, 2, or 3) is included, then the corresponding coverage reports are also split into tumor and normal files.

In somatic tumor-only mode, the reports are identical to those in germline mode and do not include tumor or normal in the file names.