The MiSeq v3.1 software updater contains the latest version of MiSeq Control Software (MCS v3.1).
For full installation instructions, see the installation notes included with the updater download package. Reference Genome v18.104.22.168 is compatible with Local Run Manager for MiSeq. Some Local Run Manager modules may require update to the Reference Genome. Refer to the module instructions on the Local Run Manager support page.
For upgrade information, see the upgrade guide notes included with the updater download package.
Note: The software updater can also be installed in the RUO drive of MiSeqDx instruments with dual boot configuration. If you are not sure if your instrument has dual boot configuration, contact Illumina Tech Support.