MiSeq Software Updater

For details about MiSeq Software Updater v2.6, see the MiSeq Software v2.6 Release Notes. For full installation instruction, see the Installation Notes included in the Updater download package. This software release continues to use the Reference Genomes v1.1.0.0 for MiSeq. If you have previously installed this version of the Reference Genomes, there is no need to update the genomes again.

Note: The software updater can also be installed in the RUO drive of MiSeqDx instruments with dual boot configuration. If you are not sure if your instrument has the dual boot upgrade, contact Illumina Technical Support. 


File Name
File Info
Date Posted
MiSeq Updater v2.6 ZIP (1 GB) 05/27/2016
MiSeq Software v2.6 Release Notes PDF (< 1 MB) 10/04/2016
MiSeq Updater v2.5.0.4 ZIP (508 MB) 09/22/2014
MiSeq Software v2.5 Release Notes PDF (< 1 MB) 09/23/2014
MiSeq Updater v2.4.1 ZIP (653 MB) 04/18/2014
MiSeq Software v2.4 Release Notes PDF (< 1 MB) 05/01/2014
Reference Genome Updater v1.1 ZIP (8 GB) 10/15/2012